Hyperhomocysteinemia is closely related to the occurrence and development of various diseases, such as cardiovascular and cerebrovascular diseases, hypertension, diabetes, kidney disease, pregnancy and other diseases, and affects almost every organ in the body. A variety of mechanisms, such as chemical and sulfur-containing compounds abnormal metabolism, affect cell function, protein synthesis and regulation, and then lead to pathological changes in tissues and organs. The causes of abnormal total homocysteine ​​metabolism are closely related to genes, nutrition, diseases, etc. The "Expert Consensus on Diagnosis and Treatment of Hyperhomocysteinemia" published in the "Electronic Journal of Tumor Metabolism and Nutrition" on September 9, 2020 》Based on a retrospective analysis of domestic and foreign research literature and evidence-based medicine in the past 30 years, combined with the characteristics of the Chinese population, the definition of hyperhomocysteinemia is given, and the dietary structure and/or the use of dietary supplements to reduce homocysteine ​​levels is proposed. Recommendations for cysteine ​​levels and the development of homocysteine-related testing indicators to clarify the cause of elevated homocysteine, and then guide precise clinical interventions to effectively improve homocysteine ​​levels. To achieve the purpose of preventing disease occurrence or delaying disease progression.