[Consensus Interpretation] Clinical tests such as blood serum, folic acid, and vitamin B12 can be carried out to clarify the cause of the elevated blood serum
Hyperhomocysteinemia is closely related to the occurrence and development of various diseases, such as cardiovascular and cerebrovascular diseases, hypertension, diabetes, kidney disease, pregnancy and other diseases, and affects almost every organ in the body. A variety of mechanisms, such as chemical and sulfur-containing compounds abnormal metabolism, affect cell function, protein synthesis and regulation, and then lead to pathological changes in tissues and organs. The causes of abnormal total homocysteine metabolism are closely related to genes, nutrition, diseases, etc. The "Expert Consensus on Diagnosis and Treatment of Hyperhomocysteinemia" published in the "Electronic Journal of Tumor Metabolism and Nutrition" on September 9, 2020 》Based on a retrospective analysis of domestic and foreign research literature and evidence-based medicine in the past 30 years, combined with the characteristics of the Chinese population, the definition of hyperhomocysteinemia is given, and the dietary structure and/or the use of dietary supplements to reduce homocysteine levels is proposed. Recommendations for cysteine levels and the development of homocysteine-related testing indicators to clarify the cause of elevated homocysteine, and then guide precise clinical interventions to effectively improve homocysteine levels. To achieve the purpose of preventing disease occurrence or delaying disease progression.
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Hyperhomocysteinemia is closely related to the occurrence and development of various diseases, such as cardiovascular and cerebrovascular diseases, hypertension, diabetes, kidney disease, pregnancy and other diseases, and affects almost every organ in the body. A variety of mechanisms, such as chemical and sulfur-containing compounds abnormal metabolism, affect cell function, protein synthesis and regulation, and then lead to pathological changes in tissues and organs. The causes of abnormal total homocysteine metabolism are closely related to genes, nutrition, diseases, etc. The "Expert Consensus on Diagnosis and Treatment of Hyperhomocysteinemia" published in the "Electronic Journal of Tumor Metabolism and Nutrition" on September 9, 2020 》Based on a retrospective analysis of domestic and foreign research literature and evidence-based medicine in the past 30 years, combined with the characteristics of the Chinese population, the definition of hyperhomocysteinemia is given, and the dietary structure and/or the use of dietary supplements to reduce homocysteine levels is proposed. Recommendations for cysteine levels and the development of homocysteine-related testing indicators to clarify the cause of elevated homocysteine, and then guide precise clinical interventions to effectively improve homocysteine levels. To achieve the purpose of preventing disease occurrence or delaying disease progression.
[World Heart Day] Pay attention to heart health, care more with hearts
World Heart Day was established by the World Heart Federation in 1999. Since 2011, World Heart Day has been held on September 29 every year, and this year's theme is "use heart to connect".
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World Heart Day was established by the World Heart Federation in 1999. Since 2011, World Heart Day has been held on September 29 every year, and this year's theme is "use heart to connect".
Three things about myocardial infarction
Cardiovascular and cerebrovascular disease is a common disease that seriously threatens human health and has become the number one killer of human health. In recent years, the incidence of acute myocardial infarction (AMI) has been on the rise in my country. Early detection and early treatment can effectively save dying myocardium, reduce infarct size, and protect cardiac function. Myocardial three items have been used more and more as a rapid auxiliary diagnosis in sudden myocardial infarction.
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Cardiovascular and cerebrovascular disease is a common disease that seriously threatens human health and has become the number one killer of human health. In recent years, the incidence of acute myocardial infarction (AMI) has been on the rise in my country. Early detection and early treatment can effectively save dying myocardium, reduce infarct size, and protect cardiac function. Myocardial three items have been used more and more as a rapid auxiliary diagnosis in sudden myocardial infarction.
[Consensus Interpretation] To protect the health of expectant mothers, Tianchen provides integrated solutions for all-scenario applications
With the increase in the proportion of late marriage, late childbearing and multiple births in my country, the incidence of PPCM has also increased significantly in recent years [2]. Cardiovascular diseases such as peripartum cardiomyopathy (PPCM) have become the main causes of death among Chinese pregnant and lying-in women in addition to obstetric factors [1]. Clinicians generally have insufficient awareness and attention to PPCM, and the rate of missed diagnosis and misdiagnosis is also high, resulting in high mortality and disability rates of PPCM in my country.
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With the increase in the proportion of late marriage, late childbearing and multiple births in my country, the incidence of PPCM has also increased significantly in recent years [2]. Cardiovascular diseases such as peripartum cardiomyopathy (PPCM) have become the main causes of death among Chinese pregnant and lying-in women in addition to obstetric factors [1]. Clinicians generally have insufficient awareness and attention to PPCM, and the rate of missed diagnosis and misdiagnosis is also high, resulting in high mortality and disability rates of PPCM in my country.
Those things about 25-0H-VD
Since the discovery of vitamin D in rickets studies in the early 20th century, important associations of vitamin D with calcium and phosphorus metabolism and bone health have continued to be discovered. Vitamin D deficiency and nutritional deficiencies are still prevalent in the population, and the serum 25-hydroxyvitamin D level of more than one billion people in the world does not reach the recommended level of 30 ng/mL (75 nmol/L) for maintaining skeletal muscle health. Chemical substances that are structurally similar to vitamin D and have active vitamin D-like effects (active vitamin D analogs) are constantly being developed and used clinically. At present, the role of vitamin D is no longer limited to regulating calcium and phosphorus metabolism and maintaining bone health, and its role in muscle, cardiovascular disease, diabetes, cancer, autoimmunity and inflammatory reactions is also increasingly corresponding. s concern.
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Since the discovery of vitamin D in rickets studies in the early 20th century, important associations of vitamin D with calcium and phosphorus metabolism and bone health have continued to be discovered. Vitamin D deficiency and nutritional deficiencies are still prevalent in the population, and the serum 25-hydroxyvitamin D level of more than one billion people in the world does not reach the recommended level of 30 ng/mL (75 nmol/L) for maintaining skeletal muscle health. Chemical substances that are structurally similar to vitamin D and have active vitamin D-like effects (active vitamin D analogs) are constantly being developed and used clinically. At present, the role of vitamin D is no longer limited to regulating calcium and phosphorus metabolism and maintaining bone health, and its role in muscle, cardiovascular disease, diabetes, cancer, autoimmunity and inflammatory reactions is also increasingly corresponding. s concern.
From "heartache" to "unable to breathe", and a brief analysis of the advantages of hs-cTn
"China Cardiovascular Disease Report 2019" shows that cardiovascular disease has become the primary cause of all-cause death in China. There are many types of diseases, and the onset is often acute and severe. In the golden time of rescue, timely diagnosis and clinical intervention are required. The urgency and necessity are much higher than other diseases. Cardiovascular-related biomarkers play an important role in this link, with the most prominent needs for the diagnosis of myocardial infarction and heart failure.
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"China Cardiovascular Disease Report 2019" shows that cardiovascular disease has become the primary cause of all-cause death in China. There are many types of diseases, and the onset is often acute and severe. In the golden time of rescue, timely diagnosis and clinical intervention are required. The urgency and necessity are much higher than other diseases. Cardiovascular-related biomarkers play an important role in this link, with the most prominent needs for the diagnosis of myocardial infarction and heart failure.
The mysterious helper in surgery
Since surgery is a typical open treatment method, it will produce a strong stress response to the patient's body itself, which will lead to the occurrence of inflammatory reaction, and will cause body damage and bleeding during the operation. Once it is not effectively controlled, postoperative Various complications may occur, a typical one being postoperative infection.
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Since surgery is a typical open treatment method, it will produce a strong stress response to the patient's body itself, which will lead to the occurrence of inflammatory reaction, and will cause body damage and bleeding during the operation. Once it is not effectively controlled, postoperative Various complications may occur, a typical one being postoperative infection.
【Consensus Interpretation】Expert consensus on the application of procalcitonin in the hierarchical management of lower respiratory tract infectious diseases in adults
Procalcitonin (PCT), an infection biomarker, can help distinguish bacterial and non-bacterial infections, help clinically safely reduce the rate of antibiotic prescriptions, shorten the duration of anti-infective treatment, and reduce the rate of bacterial resistance. However, there was no clear clinical guidance for the application of PCT in lower respiratory tract infections (LRTI) before. Application Expert Consensus in China (hereinafter referred to as the "Consensus") fills this gap.
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Procalcitonin (PCT), an infection biomarker, can help distinguish bacterial and non-bacterial infections, help clinically safely reduce the rate of antibiotic prescriptions, shorten the duration of anti-infective treatment, and reduce the rate of bacterial resistance. However, there was no clear clinical guidance for the application of PCT in lower respiratory tract infections (LRTI) before. Application Expert Consensus in China (hereinafter referred to as the "Consensus") fills this gap.
The "antibiotic restriction order" has been upgraded again, and the use of antibiotics will be included in the performance assessment of public hospitals
In order to further strengthen the management of antimicrobial drugs, actively respond to microbial resistance, and continue to improve the level of clinical rational drug use, the National Health and Health Commission issued the "Notice on Further Strengthening the Management of Antimicrobial Drugs to Curb Drug Resistance" on April 7, 2021. Looking back at the past few years, policy documents related to microbial use will be issued after the two sessions every year, and antibiotics are the most important class of anti-microbial drugs, which shows that the country attaches great importance to the management of antibiotic use.
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In order to further strengthen the management of antimicrobial drugs, actively respond to microbial resistance, and continue to improve the level of clinical rational drug use, the National Health and Health Commission issued the "Notice on Further Strengthening the Management of Antimicrobial Drugs to Curb Drug Resistance" on April 7, 2021. Looking back at the past few years, policy documents related to microbial use will be issued after the two sessions every year, and antibiotics are the most important class of anti-microbial drugs, which shows that the country attaches great importance to the management of antibiotic use.
